Categorization of diseases and traits
The categorization used by Pregenic is modelled upon ICD-11, which is the 11th revision of the International Classification of Diseases. ICD-11 is a large taxonomy with thousands of classes for diseases. This is of great help to doctors all over the world since it provides a common language for reporting and monitoring diseases. At Pregenic, we keep it at the top levels, enabling you to efficiently look through your predispositions in the different categories.
On the top level, we categorise “Organic diseases”, “Mental diseases” mapped from ICD-11. Furthermore, we provide insights into the categories “Appearance”, where we look at genetics that influence how you look and the category “Other” where we have some fun facts. Furthermore, the aim is also to show which exact categories and sub-categories we cover in our report.
This category includes all mental diseases like Alzheimer’s disease, frontotemporal dementia and schizophrenia.
|Alcohol use disorder|
|Amyotrophic lateral sclerosis|
|Attention deficit hyperactivity disorder|
|Major depressive disorder|
This category involves all traits related to appearance.
This category includes all traits that can not be fit into the other categories including snoring, coffee consumption and morningness.
|Bitter alcoholic beverage consumption|
|Bitter beverage consumption|
|Sweet beverage consumption|
The organic disease category includes diseases like allergic diseases, cancer related diseases and many more. With the view of having a better understanding, we divided this large category into smaller categories as indicated below.
This category includes all diseases related to the genitourinary system, which consists of the reproductive system and the urinary system.
|Chronic kidney disease|
|Idiopathic membranous nephropathy|
|Type 1 diabetes nephropathy|
|Type 2 diabetes nephropathy|
This category includes all the types of abnormal cell growth and tumors that we can analyse your predispositions to.
|Basal cell carcinoma|
|Chronic lymphocytic leukemia|
|Cutaneous malignant melanoma|
|Cutaneous squamous cell carcinoma|
|Diffuse large B cell lymphoma|
|Epithelial ovarian cancer|
|Esophageal squamous cell carcinoma|
|Keratinocyte cancer (MTAG)|
|Mucinous ovarian carcinoma|
|Non-small cell lung cancer|
|Ovarian cancer in BRCA1 mutation carriers|
|Primary central nervous system lymphoma|
|Renal cell carcinoma|
|Serous borderline ovarian cancer|
|Squamous cell carcinoma|
|Squamous cell lung carcinoma|
|Testicular germ cell tumor|
|Urinary bladder cancer|
This category refers to diseases caused by infections by e.g. bacteria or vira. Of course you need to be exposed to these infections for the disease to develop, however, your genetics might increase your risk of developing the disease upon exposure, due to various factors. This category includes chronic hepatitis B and C infection as well as leprosy.
|Chronic hepatitis B infection|
|Chronic hepatitis C infection|
This category includes all kinds of allergies that we can analyse your predispositions to.
|Hay fever and/or eczema|
|IgE grass sensitization|
This category refers to diseases of your immune system. This can for example be autoimmune disease or diseases that lower your immune responses.
|Autoimmune thyroid disease|
|Limited cutaneous systemic scleroderma|
|Systemic lupus erythematosus|
This category contains all the different diseases related to your respiratory system. Your respiratory system includes your airways, lungs and blood vessels.
|Chronic obstructive pulmonary disease|
|Idiopathic pulmonary fibrosis|
|Interstitial lung disease|
This category includes all diseases related to your visual system, which consists of your eyes and its related nerves.
|Age-related macular degeneration|
|Retinopathy in non-diabetics|
This category includes all the diseases related to your nervous system. Your nervous system consists of your central and peripheral nervous system.
|Carpal tunnel syndrome|
|Lewy body disease|
|Migraine without aura|
|Multiple system atrophy|
|Restless legs syndrome|
This category contains all diseases related to your circulatory system, which consists of all the blood vessels carrying blood to and from your heart. This system is responsible for carrying oxygen to your tissue and disposing of waste.
|Abdominal aortic aneurysm|
|Calcific aortic valve stenosis|
|Coronary artery calcification|
|Coronary artery disease|
|Coronary heart disease|
|Peripheral artery disease|
This category includes all diseases related to your skin.
|Cutaneous lupus erythematosus|
This category includes all diseases related to your digestive system. Your digestive system consists of your gastrointestinal tract, which is your mouth, esophagus and intestines. These are referred to as the hollow organs of your digestive system. The solid organs of your digestive system consist of your liver, pancreas and gallbladder.
|Cirrhosis (alcohol related)|
|Inflammatory bowel disease|
|Nonalcoholic fatty liver disease|
|Primary biliary cholangitis|
|Primary biliary cirrhosis|
|Primary sclerosing cholangitis|
This category includes all endocrine and metabolic diseases. The endocrine system is responsible for releasing hormones into the blood system. The metabolic system is responsible for controlling your metabolism, which serves three purposes. Conversion of food to energy (catabolism), conversion of food to building blocks for proteins, lipids etc. (anabolism) and the elimination of metabolic wastes.
|Polycystic ovary syndrome|
|Rheumatoid arthritis (ACPA-positive)|
|Type 1 diabetes|
|Type 2 diabetes|
This category includes all diseases related to the musculoskeletal system. The musculoskeletal system consists of the bones, cartilage, tendons, muscles, ligament, joints and connective tissue.
|Adolescent idiopathic scoliosis|
|Disc degeneration (lumbar)|