Categorization of diseases and traits
The categorization used by Pregenic is modelled upon ICD-11, which is the 11th revision of the International Classification of Diseases. ICD-11 is a large taxonomy with thousands of classes for diseases. This is of great help to doctors all over the world since it provides a common language for reporting and monitoring diseases. At Pregenic, we keep it at the top levels, enabling you to efficiently look through your predispositions in the different categories.
On the top level, we categorise “Organic diseases”, “Mental diseases” mapped from ICD-11. Furthermore, we provide insights into the categories “Appearance”, where we look at genetics that influence how you look and the category “Other” where we have some fun facts. Furthermore, the aim is also to show which exact categories and sub-categories we cover in our report.
Mental diseases
This category includes all mental diseases like Alzheimer’s disease, frontotemporal dementia and schizophrenia.
| Alcohol use disorder |
| Alzheimer’s disease |
| Amyotrophic lateral sclerosis |
| Anorexia nervosa |
| Attention deficit hyperactivity disorder |
| Autism |
| Bipolar disorder |
| Bulimia nervosa |
| Major depressive disorder |
| Schizophrenia |
| Tourette syndrome |
Appearance
This category involves all traits related to appearance.
| Facial wrinkles |
| Freckling |
Other
This category includes all traits that can not be fit into the other categories including snoring, coffee consumption and morningness.
| Alcohol consumption |
| Bitter alcoholic beverage consumption |
| Bitter beverage consumption |
| Cholesterol |
| Coffee consumption |
| Left-handedness |
| Morningness |
| Motion sickness |
| Neuroticism |
| Snoring |
| Sweet beverage consumption |
Organic diseases
The organic disease category includes diseases like allergic diseases, cancer related diseases and many more. With the view of having a better understanding, we divided this large category into smaller categories as indicated below.
This category includes all diseases related to the genitourinary system, which consists of the reproductive system and the urinary system.
| Chronic kidney disease |
| Endometriosis |
| Idiopathic membranous nephropathy |
| Kidney stones |
| Microalbuminuria |
| Type 1 diabetes nephropathy |
| Type 2 diabetes nephropathy |
This category includes all the types of abnormal cell growth and tumors that we can analyse your predispositions to.
| Basal cell carcinoma |
| Bladder cancer |
| Breast cancer |
| Cervical cancer |
| Chronic lymphocytic leukemia |
| Colorectal cancer |
| Cutaneous malignant melanoma |
| Cutaneous squamous cell carcinoma |
| Diffuse large B cell lymphoma |
| Endometrial cancer |
| Epithelial ovarian cancer |
| Esophageal cancer |
| Gastric cancer |
| Esophageal squamous cell carcinoma |
| Ewing sarcoma |
| Follicular lymphoma |
| Gallbladder cancer |
| Gastric cancer |
| Glioblastoma |
| Glioma |
| Hepatocellular carcinoma |
| Hodgkin’s lymphoma |
| Keratinocyte cancer (MTAG) |
| Lung adenocarcinoma |
| Lung cancer |
| Melanoma |
| Mucinous ovarian carcinoma |
| Multiple myeloma |
| Nasopharyngeal carcinoma |
| Neuroblastoma |
| Non-small cell lung cancer |
| Ovarian cancer |
| Ovarian cancer in BRCA1 mutation carriers |
| Paget’s disease |
| Pancreatic cancer |
| Primary central nervous system lymphoma |
| Prostate cancer |
| Renal cell carcinoma |
| Serous borderline ovarian cancer |
| Squamous cell carcinoma |
| Squamous cell lung carcinoma |
| Testicular germ cell tumor |
| Thyroid cancer |
| Urinary bladder cancer |
| Uterine fibroids |
| Wilms tumor |
This category refers to diseases caused by infections by e.g. bacteria or vira. Of course you need to be exposed to these infections for the disease to develop, however, your genetics might increase your risk of developing the disease upon exposure, due to various factors. This category includes chronic hepatitis B and C infection as well as leprosy.
| Chronic hepatitis B infection |
| Chronic hepatitis C infection |
| Leprosy |
| Tuberculosis |
This category includes all kinds of allergies that we can analyse your predispositions to.
| Allergic rhinitis |
| Hay fever and/or eczema |
| IgE grass sensitization |
This category refers to diseases of your immune system. This can for example be autoimmune disease or diseases that lower your immune responses.
| Autoimmune thyroid disease |
| Behcet’s disease |
| Limited cutaneous systemic scleroderma |
| Polymyositis |
| Psoriasis |
| Sjögren’s syndrome |
| Systemic lupus erythematosus |
| Systemic sclerosis |
This category contains all the different diseases related to your respiratory system. Your respiratory system includes your airways, lungs and blood vessels.
| Asthma |
| Chronic obstructive pulmonary disease |
| Idiopathic pulmonary fibrosis |
| Interstitial lung disease |
| Nasal polyps |
| Pulmonary emphysema |
This category includes all diseases related to your visual system, which consists of your eyes and its related nerves.
| Age-related macular degeneration |
| Corneal astigmatism |
| Diabetic retinopathy |
| Glaucoma |
| Myopia (pathological) |
| Refractive astigmatism |
| Retinopathy in non-diabetics |
This category includes all the diseases related to your nervous system. Your nervous system consists of your central and peripheral nervous system.
| Carpal tunnel syndrome |
| Epilepsy |
| Febrile seizures |
| Frontotemporal dementia |
| Generalized epilepsy |
| Intracerebral hemorrhage |
| Intracranial aneurysm |
| Ischemic stroke |
| Lewy body disease |
| Migraine |
| Migraine without aura |
| Multiple sclerosis |
| Multiple system atrophy |
| Myasthenia gravis |
| Narcolepsy |
| Neuritic plaque |
| Neurofibrillary tangles |
| Parkinson’s disease |
| Restless legs syndrome |
| Stroke |
This category contains all diseases related to your circulatory system, which consists of all the blood vessels carrying blood to and from your heart. This system is responsible for carrying oxygen to your tissue and disposing of waste.
| Abdominal aortic aneurysm |
| Atrial fibrillation |
| Calcific aortic valve stenosis |
| Coronary artery calcification |
| Coronary artery disease |
| Coronary heart disease |
| Hypertension |
| Myocardial infarction |
| Peripheral artery disease |
| Resistant hypertension |
| Thrombosis |
| Varicose veins |
| Venous thromboembolism |
This category includes all diseases related to your skin.
| Acne (severe) |
| Alopecia areata |
| Atopic dermatitis |
| Cutaneous lupus erythematosus |
| Male-pattern baldness |
| Psoriasis vulgaris |
| Vitiligo |
This category includes all diseases related to your digestive system. Your digestive system consists of your gastrointestinal tract, which is your mouth, esophagus and intestines. These are referred to as the hollow organs of your digestive system. The solid organs of your digestive system consist of your liver, pancreas and gallbladder.
| Barrett’s esophagus |
| Celiac disease |
| Cirrhosis (alcohol related) |
| Crohn’s disease |
| Eosinophilic esophagitis |
| Gallstone disease |
| Inflammatory bowel disease |
| Mouth ulcers |
| Nonalcoholic fatty liver disease |
| Pancreatitis |
| Periodontitis (DPAL) |
| Pit-and-Fissure caries |
| Primary biliary cholangitis |
| Primary biliary cirrhosis |
| Primary sclerosing cholangitis |
| Smooth-surface caries |
| Ulcerative colitis |
This category includes all endocrine and metabolic diseases. The endocrine system is responsible for releasing hormones into the blood system. The metabolic system is responsible for controlling your metabolism, which serves three purposes. Conversion of food to energy (catabolism), conversion of food to building blocks for proteins, lipids etc. (anabolism) and the elimination of metabolic wastes.
| Albuminuria |
| Graves’ disease |
| Hypertriglyceridemia |
| Hyperuricemia |
| Hypothyroidism |
| Metabolic syndrome |
| Obesity |
| Polycystic ovary syndrome |
| Rheumatoid arthritis (ACPA-positive) |
| Type 1 diabetes |
| Type 2 diabetes |
This category includes all diseases related to the musculoskeletal system. The musculoskeletal system consists of the bones, cartilage, tendons, muscles, ligament, joints and connective tissue.
| Adolescent idiopathic scoliosis |
| Ankylosing spondylitis |
| Disc degeneration (lumbar) |
| Dupuytren’s disease |
| Gout |
| Osteoarthritis |
| Osteoarthritis (hip) |
| Psoriatic arthritis |
| Rheumatoid arthritis |